Low Dose Naltrexone (LDN) in McAllen, Texas
Clean relief. Immune balance. Targeted wellness.
At Elite Functional Health in McAllen, Texas, we offer Low Dose Naltrexone (LDN) therapy to support immune function, reduce inflammation, and manage chronic conditions. LDN works by encouraging natural endorphin production and improving cellular health.
Many clients experience better sleep, increased energy, improved mood, and relief from chronic pain, autoimmune disorders, or fatigue. Our expert team tailors the dosage to your specific needs. Treatment is oral, well-tolerated, and easy to incorporate into daily life, with positive changes often appearing within weeks.
What Is Low Dose Naltrexone (LDN)?
Low‑Dose Naltrexone (LDN) is a therapeutic approach that uses a significantly lower dose—typically about one‑tenth or less—of the medication Naltrexone than its original use for opioid dependence (approximately 4.5 mg compared to 50–100 mg).
It works by temporarily blocking opioid receptors, prompting the body to boost natural endorphins and significantly influencing immune and inflammatory responses.
It is most often used off‑label to explore benefits in conditions such as chronic pain, autoimmune disorders, and fatigue, and while early evidence shows promise, larger clinical trials are still needed to establish its effects and safety fully.
Benefits of Low‑Dose Naltrexone (LDN)
- Reduces inflammation
- Eases chronic pain from fibromyalgia and autoimmune conditions.
- Supports better mood, mental clarity, and emotional balance.
- Improves sleep quality and helps restore natural rest cycles.
- Well-tolerated, non-addictive, and easy to take daily.
Frequently Asked Questions:
What is Low Dose Naltrexone (LDN)?
Low Dose Naltrexone is a medication originally FDA-approved at 50mg for treating opioid and alcohol addiction. When prescribed at much lower doses (typically 1.5-4.5mg), it has unique anti-inflammatory and immune-modulating effects that can help manage chronic pain, autoimmune conditions, and fatigue.
What conditions can LDN treat?
LDN is commonly used to help manage fibromyalgia, chronic fatigue syndrome, multiple sclerosis, Crohn's disease, inflammatory bowel conditions, autoimmune disorders, chronic pain, depression, anxiety, and skin conditions.
How does LDN work?
LDN temporarily blocks opioid receptors in your brain for a brief period, which triggers your body to produce a rebound surge of natural endorphins (your body's natural painkillers). This helps reduce inflammation, modulate your immune system, and relieve pain.
How long does it take for LDN to work?
Most patients begin to notice improvements within a few weeks to a couple of months after starting LDN. Some people may need up to 3 months to see full benefits. Patience is important when starting this therapy.
What are the side effects of LDN?
LDN is generally well tolerated with minimal side effects. The most common side effects include vivid dreams (which usually resolve after a few days), sleep disturbances, mild nausea, stomach cramping, or temporary flu-like symptoms. Most side effects are mild and short-lived.
Can I take LDN with other medications?
LDN should NOT be taken with opioid pain medications, as it blocks opioid receptors and can cause withdrawal symptoms. It's generally safe with most other medications, but you should tell your healthcare provider about all medications and supplements you're taking. Some patients on thyroid medication may need closer monitoring.
Is LDN addictive or habit-forming?
No, LDN is not addictive or habit-forming. You can stop taking LDN without experiencing withdrawal symptoms. However, you should always consult your healthcare provider before stopping or changing your dose.
Patient Satisfaction Is Our Priority 
I came to Dr Tagle a broken shell of myself. I no longer recognized my body—or even my personality. From the very beginning, the team reassured me that within 12 weeks I would start feeling better, but it didn’t take nearly that long.
By week six, my health had completely turned around. I had hope again. My brain felt like it was connecting, my feet were finally on solid ground, and my health was moving in the right direction. For the first time in a long time, I felt like myself again.
What stood out most was the thoughtful, root-cause approach to healing—without the endless pharmaceuticals, referrals, and testing that conventional medicine so often relies on. I felt truly seen, heard, and guided with intention.
I am deeply grateful for the care, expertise, and compassion I received. This experience truly gave me my life back.
Me, my son and my husband Joe leave his office not only with fewer prescriptions, but with a heart full of hope and a clear plan to defy the odds. The results speak for themselves.
His entire staff is incredibly competent and clearly loves and respects him as much as his patients do, which creates such a warm and positive environment.
Dr. Tagle and his wife Marissa Tagle PA, are a true gift to the RGV community, healing bodies and blessing families with their functional medicine approach.
I highly recommend them to anyone seeking true health restoration.
Excellent service.
